THE EFFECTS OF ANTIGENS AND OF PHYTOHEMAGGLUTININ ON RABBIT SPLEEN CELL SUSPENSIONS
نویسندگان
چکیده
منابع مشابه
The Effects of Antigens and of Phytohemagglutinin on Rabbit Spleen Cell Suspensions
Phytohemagglutinin (PHA) stimulated the rate of DNA synthesis in rabbit spleen cell suspensions. Unlike antigens, previous immunization to PHA was not necessary and the specific response could not be transferred by macrophages, although lymphocytes primed by incubation in PHA were able to stimulate other spleen cells not directly exposed to PHA. When rabbits were stimulated by in vivo immunizat...
متن کاملThe Effects of Antigens and of Phytohemagglutinin on Rabbit Spleen Cell Suspensions by G. Harris,* M.b., and R. J. Littleton
Phytohemagglutinin (PHA) was first shown to be an initiator of mitosis in cultures of normal human leukocytes from peripheral blood (1). Evidence has been presented (2) that the responding cells from human blood had the characteristics of lymphocytes and were derived from a nondividing population. This has been confirmed by other studies (3, 4) which showed that small lymphocytes transformed in...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1966
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.124.4.621